Starting with a two dose simulation, with a lag time. The first dose starts at the lag time, here 0.2 hr. The second dose given at 4 hours is specified as 4.2 (i.e. 4 + lag time). Let's add two more doses at 8 and 12 hr. That is, at 8.2 and 12.2. Note times are type 0 parameter and doses are type 1. Also specify all (if possible) invariant parameters before specifying time. The .BAT file snippet below describes four parameters, two for each dose. To add two additonal doses copy these 20 lines and paste them after the last line shown. Note the '--' is used here to separate parameter details and is not included in the .BAT file.
--
0 Parameter type <- a Time
FirstDoseTime
0.2000 Parameter value
0 happy or not <- end of FirstDoseTime
--
0 Parameter type <- a Time
SecondDoseTime
4.200 Parameter value
0 happy or not <- end of SecondDoseTime
--
1 Parameter type <- a Dose
DoseOne
250.0 Parameter value
1 Start interrupt number <- given at the first Time
1 To
0 happy or not <- end of DoseOne
--
1 Parameter type <- a Dose
DoseTwo
250.0 Parameter value
2 Start interrupt number <- given at the second Time
1 To
0 happy or not <- end of DoseTwo
--
This will result in 40 lines as shown below
0 Parameter type
FirstDoseTime
0.2000 Parameter value
0 happy or not
0 Parameter type
SecondDoseTime
4.200 Parameter value
0 happy or not
1 Parameter type
DoseOne
250.0 Parameter value
1 Start interrupt number
1 To
0 happy or not
1 Parameter type
DoseTwo
250.0 Parameter value
2 Start interrupt number
1 To
0 happy or not
0 Parameter type
FirstDoseTime
0.2000 Parameter value
0 happy or not
0 Parameter type
SecondDoseTime
4.200 Parameter value
0 happy or not
1 Parameter type
DoseOne
250.0 Parameter value
1 Start interrupt number
1 To
0 happy or not
1 Parameter type
DoseTwo
250.0 Parameter value
2 Start interrupt number
1 To
0 happy or not
Now edit the later 20 lines.
Change FirstDoseTime to 3rdDoseTime
Change 0.2000 to 8.2, the third dose time plus lag time
Change SecondDoseTime to 4thDoseTime
Change 4.2 to 12.2, the fourth dose time plus lag time
Change DoseOne to DoseThree
Change 1 to 3, to point to the third type 0 parameter
Change DoseTwo to DoseFour
Change 2 to 4, to point to the fourth type 0 parameter
This should result in these new lines
0 Parameter type
FirstDoseTime
0.2000 Parameter value
0 happy or not
0 Parameter type
SecondDoseTime
4.200 Parameter value
0 happy or not
1 Parameter type
DoseOne
250.0 Parameter value
1 Start interrupt number
1 To
0 happy or not
1 Parameter type
DoseTwo
250.0 Parameter value
2 Start interrupt number
1 To
0 happy or not
0 Parameter type
3rdDoseTime
8.2000 Parameter value
0 happy or not
0 Parameter type
4thDoseTime
12.20 Parameter value
0 happy or not
1 Parameter type
DoseThree
250.0 Parameter value
3 Start interrupt number
1 To
0 happy or not
1 Parameter type
DoseFour
250.0 Parameter value
4 Start interrupt number
1 To
0 happy or not
IMPORTANT Save the edited file as plain ascii text with the .BAT extension.
A data set included within a .BAT file might look like this for a simulation.
1 Data from disk or keyboard
0.000 X value
0.000 Y value
0.2500 X value
0.000 Y value
0.5000 X value
0.000 Y value
1.000 X value
0.000 Y value
2.000 X value
0.000 Y value
3.000 X value
0.000 Y value
4.000 X value
0.000 Y value
6.000 X value
0.000 Y value
9.000 X value
0.000 Y value
12.00 X value
0.000 Y value
18.00 X value
0.000 Y value
24.00 X value
0.000 Y value
-1.000 X value
Each data point consists of two lines. One for the x value and one the y value. Include decimal points. End the data with x = -1.
IMPORTANT Save the edited file as plain ascii text with the .BAT extension.