Description and quantitation of factors affecting the absorption, distribution, and metabolism, and excretion of drugs. Development of appropriate dosage regimens and graphical analysis of drug concentration data sets. Bioequivalence and drug product testing. Drug analysis in biological matrix.
Application of biopharmaceutical and pharmacokinetic theory to clinical problems involved in optimizing and monitoring drug use in patients
Course Objectives
Students will be able to:
Demonstrate an understanding of the differential and integrated equations associated with pharmacokinetic models
Demonstrate an understanding and assess factors which affect the absorption, distribution, metabolism and excretion of drugs
Calculate parameter values from appropriate data using graphical techniques
Calculate appropriate dosing regimens using appropriate criteria
Describe the techniques used to determine drug concentrations in biological and formulation matrices